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Description

Under mild oxidative stress the oxidation of thiol residues favors the recruitment of Hsp90 thereby protecting SENP3 from binding to CHIP, which results in its ubiquitination and subsequent elimination via proteasomal degradation

2024: Neurology Live

Antioxid Basel Switz (2021) 10:1867

Cheah IK, Ong RL, Gruber J et al (2013) Knockout of a putative Ergothioneine transporter in Caenorhabditis elegans decreases lifespan and increases susceptibility to oxidative damage